Anti-infectives covers what is commonly known as Systemic Antibiotics, which are medications which treat infection. Newer antibiotic are designed to provide broad spectrum cover.
The most famous and first antibiotic was discovered in 1929 by Sir Alexander Fleming, when he observed the inhibition of Staphylococci contaminated by the Penicillin mould. By the mid 1940s, antibiotics were available for the treatment of various bacterial infections including those of the throat and skin, pneumonia, Scarlet Fever, infected wounds amongst others. The 1950s saw the introduction of Streptomycin, Tetracycline and others leading to the effective treatment of what were formerly life-threatening infections.
Antibiotics are divided into different classes depending on their specific properties and modes of action, and they can be administered via injection or orally.
The three different classes of antibiotics GSK produces are:
- Broad Spectrum Penicillin – Amoxycilin and Clavulanic Acid (oral / injection)
- Cephalosporin – divided into three generations:
- 1st Generation – Cephlaxin (oral)
- 2nd Generation – Cefuroxime Axetil (oral) and Cefuroxime Sodium (via injection)
- 3rd Generation – Ceftazidime (via injection)
- Trimethoprim / Sulphamethoxazole – Trimethoprim combinations (oral / injection)
GSK takes consumer healthcare very seriously and understands precisely what the consumer wants and needs. With nearly US$5 billion in sales and over ten US$100 million brands found worldwide, GSK is a dominant player in the market bringing over-the-counter (OTC) medication, oral healthcare and nutritional healthcare to millions of people.